Fat soluble vitamins : Vit A [ part 1 ]
Biochemistry

Fat soluble vitamins : Vit A [ part 1 ]

    Hlw Guys,  In the previous post we knew about vitamins & its classification. 


    Today we discuss about    a fat soluble vitamins : Vit A

      

    ★ Criteria Fat SolubleVitamins


      Soluble in organic or fat solvent (Benzene/ Ether)

      Released, absorbed, transported with fat diet

      Not readily excreted in urine

      Stored in liver & adipose tissue

      Only vitamin K has coenzyme activity

      Have toxic effect if intake is more than RDA (vitA, vitD)

      Deficiency features develop slowly than water soluble vitamins.


    ★ Retinoids(Preformed vitamin 


    1.Retinol

    * Alcohol

    * Storage form of vitamin 

    2.Retinal

    * Aldehyde derivative of retinol

    * Retinol ↔retinal

    3.Retinoic acid

    * Acid

    * Retinol

    * Retinoic acid

                        👉👉RDA 👈👈

                   1.  Adult male900 RAE
                   2.  Adult female700 RAE

           ★Functions of Vitamin A★


    •Maintain reproductionby supporting spermatogenesis in male

    •prevention of fetal resorptionin female.   

    •Maintain visionby formation of visual pigment ‘Rhodopsin’ in retina.

    •Promotion of growth

    •Maintain integrity of epithelial tissue

    •Epithelial tissue differentiation& mucous secretion

    •Gene expression

    •Promotion of growth

    •Have role in cancer prevention

    •Antioxidant

    •prevent cancer & heart disease

            ★ Vitamin A deficiency ★  


    * Loss of sensitivity to green light (earliest sign)

    * Impairment to adapt dim light

    * Night blindness 

    * Xerophthalmia(in prolonged deficiency)

    * Keratinization of cornea

    * Blindness

    * Increased susceptibility to infectious disease

    * Keratinization of skin

    * Atrophy of epithelium

    * Growth retardation

    That's all for today guys. 

    In the next articles we will discuss about onother fat soluble vitamins 

    Vit D.

    Till then Good luck.

    STAY WITH US.

    IF ANY DOUBT,  DON’THESITANT TO COMMENT. 

    THANK YOU.          



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